The Outbreak Prevention and Investigation research group is at the forefront of research focused on understanding zoonotic disease spillover mechanisms in the natural environment. With a strong emphasis on biosafety and field virology, our research group is dedicated to investigating the spillover mechanisms of highly pathogenic viruses, including Nipah virus and various filoviruses. One of our notable achievements includes being the first to successfully isolate the Lloviu virus, a member of the filovirus family. This groundbreaking accomplishment has provided valuable insights into the characteristics and behavior of this virus, contributing to our understanding of filoviruses and their potential impact on human and animal health. By combining expertise in biosafety practices and field-based virology, our research group strives to uncover the intricate dynamics of zoonotic disease transmission, shedding light on the factors that contribute to spillover events. Through our research projects, we aim to enhance our knowledge of high-risk viruses and develop strategies for effective outbreak prevention and control. The Outbreak Prevention and Investigation research group at the University of Pécs National Laboratory of Virology is committed to advancing scientific understanding, promoting biosafety practices, and ultimately mitigating the risks posed by zoonotic diseases.